This is an excellent question and an age old question as well. Getting rid of fleas on the puppy is easy! Getting rid of the fleas in the environment and preventing re-infection is a larger committment. Here is the magic formula... ready...? Today, veterinarians have some great flea control products we can use. We have products that treat all stages of the flea's life cycle, which really gets rid of them for good (including re-exposure under most circumstances). There are now several highly efficacious, long lasting and very safe new products to choose from. It is best to discuss with your vet and get their recommendations, but here is a good option: In kittens or puppies younger than 8 weeks, treating the environment very well with thorough area vaccuuming (throw away the bag immediately afterwards), boric acid powder (completely safe for people and pets, but not insects) in the house and on furniture and bathing the pet with a regular dog shampoo and manually removing the dead or live fleas with a flea comb is the safest way to go. This can be done in any aged pet, but, for the best most consistent results after 8 weeks of age, i would recommend the following protocol: Initially, in puppies over 8 weeks and Adult dogs you should get fipronil (Frontline Spray or Frontline Plus®) or imidacloprid (Advantage®) drip-on from your vet and use this. Additionally, it should be used regularly to keep the fleas off and away for good.